Brukinsa is a small molecule Bruton tyrosine kinase (BTK) inhibitor developed by BeiGene scientists and is used in clinical programs worldwide as monotherapy or in combination with other agents to treat B-cell malignancies. Because the novel BTK is continuously synthesized, Brukinsa was specifically designed to provide complete and sustained inhibition of the BTK protein through enhanced bioavailability, half-life, and selectivity. Its pharmacokinetics are distinct from other approved BTK inhibitors, and Brukinsa inhibits malignant B-cell proliferation in a range of disease-relevant tissues.
It is used to treat adult patients with marginal zone lymphoma, chronic lymphocytic leukemia (CLL), or small lymphocytic lymphoma (SLL) in adults.
Active ingredient: zanubrutinib
Prescription drug
It is possible to order from Germany