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Champix (Chantix) is highly selective and binds to a greater extent to the α4β2 receptor subtype than to other nicotinic receptor subtypes (α3β4, α7, α1βγδ) or other receptors and transport proteins. The effectiveness of varenicline as a treatment for nicotine addiction is due to its partial agonism of the α4β2 nicotinic receptor, binding to which reduces the craving for smoking and alleviates the manifestation of the withdrawal syndrome, while simultaneously reducing the feeling of pleasure from smoking (antagonism in the presence of nicotine).
Used as a means of quitting smoking in adults aged 18 years and older, without age restrictions.
Active ingredient: varenicline
Prescription medicine
